MEF2D Antibody - middle region (ARP38699_P050)

Catalog No: ARP38699_P050

WB Suggested Anti-MEF2D Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human kidney

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MEF2D
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: GDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLD
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MEF2D (ARP38699_P050) antibody is Catalog # AAP38699 (Previous Catalog # AAPP20888)

Target Info

• Gene Symbol: MEF2D
• Gene Full Name: Myocyte enhancer factor 2D
• Alias Symbols: DKFZp686I1536
• NCBI Gene Id: 4209
• Protein Name: Myocyte-specific enhancer factor 2D
• Description of Target: MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.MEF2D plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.MEF2D plays a critical role in the regulation of neuronal apoptosis.
• Uniprot ID: Q14814
• Protein Accession #: NP_005911
• Nucleotide Accession #: NM_005920
• Protein Size (# AA): 521
• Molecular Weight: 56kDa
• Protein Interactions: SUMO1; CDK6; ASCL1; APP; SUMO2; UBC; CABIN1; MEF2A; HDAC1; HIRA; ASH2L; KMT2D; RBBP5; MEN1; PRKACA; SENP3; HDAC4; COPS5; CARM1; PRMT5; KAT2B; HDAC3; SNCA; MAPK14; HDAC5; EP300; MAPK7; CASP7; MEF2D; MEF2C; NFATC2; SP1; YWHAQ;