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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

ME1 antibody - N-terminal region (ARP32794_P050)

100 ul
$289.00
In Stock

Conjugation Options

ARP32794_P050-FITC Conjugated

ARP32794_P050-HRP Conjugated

ARP32794_P050-Biotin Conjugated

Gene Symbol:
ME1
NCBI Gene Id:
4199
Official Gene Full Name:
Malic enzyme 1, NADP(+)-dependent, cytosolic
Protein Name:
NADP-dependent malic enzyme
Swissprot Id:
P48163
Protein Accession #:
NP_002386
Nucleotide Accession #:
NM_002395
Alias Symbols:
HUMNDME, MES
Replacement Item:
This antibody may replace item sc-100569, HPA006493
Description of Target:
ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Size (# AA):
572
Molecular Weight:
64kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ME1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ME1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human ME1
Species Reactivity:
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Dog: 85%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 91%; Rabbit: 100%; Rat: 100%; Sheep: 92%
Complete computational species homology data:
Anti-ME1 (ARP32794_P050)
Peptide Sequence:
Synthetic peptide located within the following region: QQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; VTA1; RPUSD2; GORASP2; BOP1; TOM1; NMI; CUL3; UGDH; TBCD; GTF2A1; GARS; CTTN;
Blocking Peptide:
For anti-ME1 (ARP32794_P050) antibody is Catalog # AAP32794 (Previous Catalog # AAPP03813)
Datasheets/Manuals:
Printable datasheet for anti-ME1 (ARP32794_P050) antibody
Sample Type Confirmation:

ME1 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Target Reference:
Hsieh,J.Y., (2006) J. Biol. Chem. 281 (32), 23237-23245

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