Catalog No: OPCA02577
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OPCA02577
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Product Info
Predicted Species ReactivityEntamoeba histolytica
Product FormatLiquid or Lyophilized powder
HostEntamoeba histolytica
Additional InformationRelevance: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Reconstitution and Storage-20°C or -80°C
Formulation20 mM Tris-HCl based buffer, pH 8.0
PurityGreater than 90% as determined by SDS-PAGE.
Peptide SequenceSGCGKSTTIQLIQRNYEPNGGRVTLDGKDIRELNIKWLRNQIGLVGQEPVLFAGTIRENIMLGAKEGETLSKDEMIECAKMANAHEFVSKLAEGYDTLIGEKGALLSGGQRQRI
Protein SequenceSGCGKSTTIQLIQRNYEPNGGRVTLDGKDIRELNIKWLRNQIGLVGQEPVLFAGTIRENIMLGAKEGETLSKDEMIECAKMANAHEFVSKLAEGYDTLIGEKGALLSGGQRQRI
Storage BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
SourceYeast
Protein Range1-114 aa
TagN-terminal 6xHis-tagged
ReferenceEmetine-resistant mutants of Entamoeba histolytica overexpress mRNAs for multidrug resistance.Samuelson J., Ayala P., Orozco E., Wirth D.Mol. Biochem. Parasitol. 38:281-290(1990)
Gene SymbolMDR1
Alias SymbolsP-glycoprotein.
Protein NameMultidrug resistance protein 1
Description of TargetEnergy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Uniprot IDP16875
Protein Size (# AA)Recombinant
Molecular Weight14.5 kda
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