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Mdm2 Antibody (OASA08459)

50 ug
$410.00
In Stock
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Gene Symbol:
Mdm2
NCBI Gene Id:
17246
Protein Name:
E3 ubiquitin-protein ligase Mdm2
Swissprot Id:
P23804
Protein Accession #:
NP_034916.1
Alias Symbols:
Mdm-2, AA415488, 1700007J15Rik, Mdm2
Replacement Item:
This antibody may replace item sc-13161 from Santa Cruz Biotechnology.
Description of Target:
RABBIT ANTI MOUSE MDM2
Protein Size (# AA):
489
Host:
Rabbit
Clonality:
Polyclonal
Application:
ELISA, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express Mdm2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express Mdm2.
Immunogen:
The immunogen for anti-Mdm2 antibody: synthetic peptide corresponding to aa 177-195 of mouse Mdm2.
Predicted Species Reactivity:
Mouse
Predicted Homology Based on Immunogen Sequence:
Mouse
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Datasheets/Manuals:
Printable datasheet for anti-Mdm2 antibody - OASA08459
Specificity:
MDM2
Isotype:
Polyclonal IgG
Application Info:
ELISA:    1/3000 - 1/12000
Western Blotting:    1/500 - 1/2000
:::
Preservative Stabilisers: 0.01% - Sodium Azide (NaN3)
Antiserum Preparation: Antisera to Mdm2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
:::
Approx Protein Conc: IgG concentration 0.5mg/ml
Buffer Solutions: Phosphate buffered saline pH7.2
Target Reference:
1. Sdek, P. et al. (2004) The Central Acidic Domain of MDM2 Is Critical in Inhibition of Retinoblastoma-mediated Suppression of E2F and Cell Growth. J. Biol. Chem. 279: 53317 - 53322.
2. Feng J. et al. (2004) Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation. J. Biol. Chem. 279(34):35510-7.

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