MCM3AP Antibody (OAAJ01764)

Catalog No: OAAJ01764

Size:100 ul

Western blot analysis on NIH-3T3 cell lysate using GANP Antibody

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Stable for 12 months from date of receipt.
• Immunogen: A synthesized peptide derived from human GANP
• Purification: Affinity-chromatography
• Concentration: 1 mg/ml
• Specificity: GANP antibody detects endogenous levels of total GANP
• Application Info: WB: 1:500~1:3000 IHC: 1:50~1:200

Target Info

• Gene Symbol: MCM3AP
• Gene Full Name: minichromosome maintenance complex component 3 associated protein
• Alias Symbols: GANP, SAC3, MAP80, PNRIID
• NCBI Gene Id: 8888
• Description of Target: GANP is a member of the SAC3 family of nuclear export factors. In combination with ENY2, PCID2 and centrins, forms the TREX-2 complex that links transcription/ processing with nuclear mRNA export. GANP, required to recruit ENY2 to nuclear pore complexes (NPCs), requires both its CID and MCM3AP domains, together with nucleoporin Nup153, for recruitment to NPCs. The MCM3AP domain, corresponding to the carboxy-terminal 721 amino acids of GANP, shows homology with the Gcn5-related N acetyltransferase superfamily. The protein MCM3AP is encoded entirely within the 3? region of the GANP gene. MCM3AP transcription begins within intron 16 of GANP immediately upstream of the first MCM3AP exon, where NF-IL6, AP-1, NF-?B, and p53 consensus transcription factor binding sites are located.
• Uniprot ID: O60318
• Molecular Weight: 218 kDa