MCM2 Antibody (OAAB19721)

Catalog No: OAAB19721

Size:100ul

All lanes: Anti-MCM2 Antibody at 1: 4000 dilution
Lane 1: Hela whole cell lysates
Lane 2: MCF-7 whole cell lysates
Lysates/proteins at 20 ug per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution
Predicted band size: 102 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.

Product Info

• Predicted Species Reactivity: Human
• Product Format: 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, ICC, IHC-P
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Application Info: WB: 1:4000
• Reference: Todorov I.T.,et al.J. Cell Sci. 107:253-265(1994).
  Nomura N.,et al.DNA Res. 1:27-35(1994).
  Mimura S.,et al.Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
  Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
  Mincheva A.,et al.Cytogenet. Cell Genet. 65:276-277(1994).
  

Target Info

• Gene Symbol: MCM2
• Alias Symbols: BM28, CCNL1, CDCL1, cdc19, DFNA70, D3S3194, MITOTIN
• NCBI Gene Id: 4171
• Description of Target: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
• Uniprot ID: P49736
• Molecular Weight: 102 kDa