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Catalog No: ARP51632_P050
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ARP51632_P050
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Datasheets/ManualsPrintable datasheet for anti-MBNL2 (ARP51632_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human MBNL2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Peptide SequenceSynthetic peptide located within the following region: ENGRVIACFDSLKGRCSRENCKYLHPPTHLKTQLEINGRNNLIQQKTAAA
Concentration0.5 mg/ml
Blocking PeptideFor anti-MBNL2 (ARP51632_P050) antibody is Catalog # AAP51632 (Previous Catalog # AAPP30130)
Sample Type Confirmation

There is BioGPS gene expression data showing that MBNL2 is expressed in HeLa

Gene SymbolMBNL2
Gene Full NameMuscleblind-like splicing regulator 2
Alias SymbolsMBLL, MBLL39, PRO2032
NCBI Gene Id10150
Protein NameMuscleblind-like 2 (Drosophila), isoform CRA_b EMBL EAX08969.1
Description of TargetMBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
Uniprot IDO95205
Protein Accession #NP_005748
Nucleotide Accession #NM_005757
Protein Size (# AA)255
Molecular Weight28kDa
Protein InteractionsBMI1; ELAVL1; UBC;
  1. What is the species homology for "MBNL2 Antibody - middle region (ARP51632_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "MBNL2 Antibody - middle region (ARP51632_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MBNL2 Antibody - middle region (ARP51632_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MBNL2 Antibody - middle region (ARP51632_P050)"?

    This target may also be called "MBLL, MBLL39, PRO2032" in publications.

  5. What is the shipping cost for "MBNL2 Antibody - middle region (ARP51632_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MBNL2 Antibody - middle region (ARP51632_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MBNL2 Antibody - middle region (ARP51632_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "28kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MBNL2 Antibody - middle region (ARP51632_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MBNL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MBNL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MBNL2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MBNL2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MBNL2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MBNL2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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