- Gene Symbol:
- MBNL1
- NCBI Gene Id:
- 4154
- Official Gene Full Name:
- Muscleblind-like splicing regulator 1
- Protein Name:
- MBNL1 protein EMBL AAH50535.1
- Swissprot Id:
- Q86VM6
- Protein Accession #:
- AAH50535
- Nucleotide Accession #:
- NM_021038
- Alias Symbols:
- EXP, MBNL, EXP35, EXP40, EXP42
- Replacement Item:
- This antibody may replace item sc-115973 from Santa Cruz Biotechnology.
- Description of Target:
- MBNL1 contains 4 C3H1-type zinc fingers and binds to CUG triplet repeat expansion dsRNA.
- Protein Size (# AA):
- 343
- Molecular Weight:
- 38kDa
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Purification:
- Affinity Purified
- Application:
- IHC, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express MBNL1.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express MBNL1.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human MBNL1
- Tested Species Reactivity:
- Human
- Predicted Homology Based on Immunogen Sequence:
- Dog: 100%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
- Complete computational species homology data:
- Anti-MBNL1 (ARP41227_P050)
- Peptide Sequence:
- Synthetic peptide located within the following region: AMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGI
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein Interactions:
- DAB1; AES; AEN; UBC; ABI3BP; ZNHIT3; VCAM1; ITGA4; IDH3A; FN1; TIAL1; APP; BIN1; ITSN2; DDX17; HNRNPL; HNRNPK; HNRNPH3; HNRNPH2; HNRNPH1; HNRNPF; HNRNPA2B1; DHX9; DDX5;
- Blocking Peptide:
- For anti-MBNL1 (ARP41227_P050) antibody is Catalog # AAP41227 (Previous Catalog # AAPS01306)
- Datasheets/Manuals:
- Printable datasheet for anti-MBNL1 (ARP41227_P050) antibody
- Sample Type Confirmation:
MBNL1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat
- Target Reference:
- Strausberg,R., (2003) Direct Submission
- Publications:
Coram, RJ; Stillwagon, SJ; Guggilam, A; Jenkins, MW; Swanson, MS; Ladd, AN; Muscleblind-like 1 is required for normal heart valve development in vivo. 15, 36 (2015). IHC, WB, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish 26472242
Product Reviews
- Protocol:
- Tips Information:
See our General FAQ page.
