MBL2 Antibody - C-terminal region (OAAB10036)

Catalog No: OAAB10036

Size:400ul

MBL2 Antibody (C-term) (Cat. #OAAB10036) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the MBL2 antibody detected the MBL2 protein (arrow).

Western blot analysis of MBL2 (arrow) using rabbit polyclonal MBL2 Antibody (C-term) (Cat. #OAAB10036). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MBL2 gene.

MBL2 Antibody (C-term) (Cat. #OAAB10036)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of MBL2 Antibody (C-term)(Cat#OAAB10036) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IF, IHC
• Additional Information: Precautions: MBL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA
  Cellular Location: Secreted.
  Tissue Location: Plasma protein produced mainly in the liver.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This MBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the C-terminal region of human MBL2.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IF: 1:10~50
  IHC-P: 1:10~50

Target Info

• Gene Symbol: MBL2
• Alias Symbols: MBL, MBP, MBP1, MBPD, MBL2D, MBP-C, COLEC1, HSMBPC
• NCBI Gene Id: 4153
• Protein Name: Mannose-binding protein C
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P11226
• Protein Accession #: NP_000233.1
• Molecular Weight: 26144 Da