MBL Recombinant Protein (Bovine) (OPCA03674)

Catalog No: OPCA03674

Product Info

• Predicted Species Reactivity: Bos taurus|Bovine
• Product Format: Liquid or Lyophilized powder
• Host: Bovine
• Additional Information: Relevance: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages
• Reconstitution and Storage: -20°C or -80°C
• Formulation: 20 mM Tris-HCl based buffer, pH 8.0
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: DTETENCENIRKTCPVIACGPPGINGIPGKDGRDGAKGEKGEPGQGLRGSQGPPGKMGPQGTPGIPGIPGPIGQKGDPGENMGDYIRLATSERATLQSELNQIKNWLIFSLGKRVGKKAFFTNGKKMPFNEVKTLCAQFQGRVATPMNAEENRALKDLVTEEAFLGITDQETEGKFVDLTGKGVTYQNWNDGEPNNASPGEHCVTLLSDGTWNDIACSASFLTVCEFSL
• Protein Sequence: DTETENCENIRKTCPVIACGPPGINGIPGKDGRDGAKGEKGEPGQGLRGSQGPPGKMGPQGTPGIPGIPGPIGQKGDPGENMGDYIRLATSERATLQSELNQIKNWLIFSLGKRVGKKAFFTNGKKMPFNEVKTLCAQFQGRVATPMNAEENRALKDLVTEEAFLGITDQETEGKFVDLTGKGVTYQNWNDGEPNNASPGEHCVTLLSDGTWNDIACSASFLTVCEFSL
• Storage Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Source: Mammalian Cells
• Protein Range: 21-249 aa
• Tag: N-terminal Flag-Myc-tagged

Target Info

• Reference: Cloning and characterization of a cDNA encoding bovine mannan-binding protein.Kawai T., Suzuki Y., Eda S., Ohtani K., Kase T., Fujinaga Y., Sakamoto T., Kurimura T., Wakamiya N.Gene 186:161-165(1997)
• Gene Symbol: MBL2
• Gene Full Name: mannose binding lectin 2
• Alias Symbols: mannan-binding protein;mannose-binding lectin (protein C) 2, soluble (opsonic defect);mannose-binding lectin-C;mannose-binding protein C;MBL;MBP-C;soluble mannose-binding lectin.
• NCBI Gene Id: 281297
• Protein Name: Mannose-binding protein C
• Description of Target: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
• Uniprot ID: O02659
• Protein Accession #: NP_776532.1
  
• Nucleotide Accession #: NM_174107.2
• Protein Size (# AA): Recombinant
• Molecular Weight: 28.9 kDa