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MBD1 Antibody (OADC00173)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
Unconjugated
Application:
CHIP, WB
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-10751 from Santa Cruz Biotechnology.
Purification:
Affinity purified
Predicted Homology Based on Immunogen Sequence:
Mouse
Concentration:
0.7 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-MBD1 (OADC00173) antibody
Preservative:
0.05% Sodium Azide and 0.05% ProClin 300.
Specificity:
Polyclonal antibody raised in rabbit against human MBD1 (Methyl-CpG-binding domain protein 1), using a KLH-conjugated synthetic peptide containing a sequence from the N-terminal part of the protein.
Application Info:
CHIP: 1.5 ug/CHIP
ELISA: 1:1,000
Western Blotting: 1:500
Gene Symbol:
MBD1
Official Gene Full Name:
methyl-CpG binding domain protein 1
Alias Symbols:
RFT, PCM1, CXXC3
NCBI Gene Id:
4152;
Protein Name:
methyl-CpG-binding domain protein 1
Description of Target:
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Swissprot Id:
Q9UIS9
Protein Accession #:
NP_001191065.1
Nucleotide Accession #:
NM_001204136.1
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MBD1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MBD1.

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