MAX Antibody - N-terminal region (P100953_P050)

Catalog No: P100953_P050

WB Suggested Anti-MAX Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysateThere is BioGPS gene expression data showing that MAX is expressed in COLO205

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Dog, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human MAX
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Dog: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%
• Peptide Sequence: Synthetic peptide located within the following region: MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKAS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MAX (P100953_P050) antibody is Catalog # AAP31308 (Previous Catalog # AAPP02058)
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that MAX is expressed in COLO205

• Reference: Faiola,F., (2007) Biochem. J. 403 (3), 397-407

Target Info

• Gene Symbol: MAX
• Gene Full Name: MYC associated factor X
• Alias Symbols: bHLHd4
• NCBI Gene Id: 4149
• Protein Name: Protein max
• Description of Target: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown. The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
• Uniprot ID: P61244
• Protein Accession #: NP_660087
• Nucleotide Accession #: NM_145112
• Protein Size (# AA): 151
• Molecular Weight: 17kDa
• Protein Interactions: USP37; UNC45A; BANP; FBXW11; MXI1; RPL35; TUBA1A; RPL34; GABBR1; FUS; FTH1; MYC; MXD1; MGA; PLIN3; HSP90AA1; TCF3; MYCN; CPSF6; ARL6IP5; KMT2D; HNRNPH2; DYNC1H1; CSTF2; SNIP1; PPP1CC; PPP1CB; PPP1CA; USF1; PCGF6; EP400; DMAP1; WDR5; BRD8; KAT5; MNT; MAX;