MAX Antibody - middle region (ARP38145_T100)

Catalog No: ARP38145_T100

WB Suggested Anti-MAX Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate

Host: Mouse
Target Name: MAX
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml

Rabbit Anti-MAX Antibody
Catalog Number: ARP38145_T100
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Nucleus
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAX
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
• Peptide Sequence: Synthetic peptide located within the following region: LQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-MAX (ARP38145_T100) antibody is Catalog # AAP38145 (Previous Catalog # AAPS04811)
• Reference: Banerjee,A., (2006) Biochemistry 45 (7), 2333-2338

Target Info

• Gene Symbol: MAX
• Gene Full Name: MYC associated factor X
• Alias Symbols: bHLHd4
• NCBI Gene Id: 4149
• Protein Name: Protein max
• Description of Target: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown.
• Uniprot ID: P61244
• Protein Accession #: NP_002373
• Nucleotide Accession #: NM_002382
• Protein Size (# AA): 160
• Molecular Weight: 18kDa
• Protein Interactions: USP37; UNC45A; BANP; FBXW11; MXI1; RPL35; TUBA1A; RPL34; GABBR1; FUS; FTH1; MYC; MXD1; MGA; PLIN3; HSP90AA1; TCF3; MYCN; CPSF6; ARL6IP5; KMT2D; HNRNPH2; DYNC1H1; CSTF2; SNIP1; PPP1CC; PPP1CB; PPP1CA; USF1; PCGF6; EP400; DMAP1; WDR5; BRD8; KAT5; MNT; MAX;