Catalog No: ARP74050_P050
Price: $0.00
SKU
ARP74050_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-MASP1 (ARP74050_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of Human MASP1
PurificationAffinity Purified
Peptide SequenceSynthetic peptide located within the following region: VGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
Concentration0.5 mg/ml
Blocking PeptideFor anti-MASP1 (ARP74050_P050) antibody is Catalog # AAP74050
Gene SymbolMASP1
Alias Symbols3MC1, MAP1, MASP, RaRF, CRARF, MASP3, MAp44, PRSS5, CRARF1
NCBI Gene Id5648
Description of TargetThis gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
Uniprot IDP48740-3
Protein Size (# AA)380
Molecular Weight41kDa
Protein InteractionsCDK19; CUL3; PDCD6IP; RPS6KA6; MAPK8IP2; NUDT21; NCK2; UFD1L; RPS6KA3; MAPK6; H2AFX; GSK3B; GADD45A; C2; SERPING1; FCN2; MBL2; C3; MASP2;
  1. What is the species homology for "MASP1 Antibody - middle region (ARP74050_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "MASP1 Antibody - middle region (ARP74050_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MASP1 Antibody - middle region (ARP74050_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MASP1 Antibody - middle region (ARP74050_P050)"?

    This target may also be called "3MC1, MAP1, MASP, RaRF, CRARF, MASP3, MAp44, PRSS5, CRARF1" in publications.

  5. What is the shipping cost for "MASP1 Antibody - middle region (ARP74050_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MASP1 Antibody - middle region (ARP74050_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MASP1 Antibody - middle region (ARP74050_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "41kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MASP1 Antibody - middle region (ARP74050_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MASP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MASP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MASP1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MASP1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MASP1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MASP1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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