MAPT Recombinant Protein (OPCD05136)

Catalog No: OPCD05136

MAPT Recombinant Protein (OPCD05136) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala92-Val400
  Subcellular Location: Membrane, Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Mapt
• Gene Full Name: microtubule-associated protein tau
• Alias Symbols: AI413597;AW045860;microtubule-associated protein tau;Mta;Mtapt;neurofibrillary tangle protein;paired helical filament-tau;PHF-tau;Ta;Tau.
• NCBI Gene Id: 17762
• Protein Name: Microtubule-associated protein tau
• Description of Target: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
• Uniprot ID: P10637
• Protein Accession #: NP_001033698.1
• Nucleotide Accession #: NM_001038609.2
• Protein Size (# AA): Ala92~Val400
• Molecular Weight: 44kDa