MAPKAPK2 Antibody (Phospho-Thr222) (OASG04352)

Catalog No: OASG04352

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Monkey
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human MAPKAPK-2 around the phosphorylation site of T222. Location: 160-240aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Thr222
• Specificity: Phospho-MAPKAPK-2 (T222) Polyclonal Antibody detects endogenous levels of MAPKAPK-2 protein only when phosphorylated at T222.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: MAPKAPK2
• Gene Full Name: mitogen-activated protein kinase-activated protein kinase 2
• Alias Symbols: MK2, MK-2, MAPKAP-K2
• NCBI Gene Id: 9261; 17164;
• Description of Target: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
• Uniprot ID: P49137, P49138
• Molecular Weight: 45 kDa