Catalog No: OABF01574
Size:100UL
Price: $438.00
SKU
OABF01574
Availability: 3 to 5 business days.
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)
Product Info
Predicted Species ReactivityBovine|Dog|Human|Mouse|Rabbit|Rat
Product FormatLiquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
Additional InformationSubcellular location: Cytoplasm, Nucleus
::Modification: Phosphorylation (Ser731, Thr733)
Reconstitution and Storage-20°C
ImmunogenKLH conjugated synthetic phosphopeptide derived from human ERK5 around the phosphorylation sites of Ser731+Thr733
PurificationProtein A Purified
Concentration1 ug/ul
Application InfoWB: 1:100 - 1000
IHC-P: : 1:100 - 500
Gene SymbolMAPK7
Gene Full Namemitogen-activated protein kinase 7
Alias Symbolsbig MAP kinase 1;BMK1;BMK-1;BMK1 kinase;ERK4;ERK5;ERK-5;Extracellular signal-regulated kinase 5;extracellular-signal-regulated kinase 5;MAP kinase 7;MAPK 7;mitogen-activated protein kinase 7;PRKM7.
NCBI Gene Id5598
Protein NameMitogen-activated protein kinase 7
Description of TargetPlays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.
Uniprot IDQ13164
  1. What is the species homology for "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Dog|Human|Mouse|Rabbit|Rat".

  2. How long will it take to receive "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)"?

    This item is available "3 to 5 business days.".

  3. What buffer format is "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)" provided in?

    This item is provided in "Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)"?

    This target may also be called "big MAP kinase 1;BMK1;BMK-1;BMK1 kinase;ERK4;ERK5;ERK-5;Extracellular signal-regulated kinase 5;extracellular-signal-regulated kinase 5;MAP kinase 7;MAPK 7;mitogen-activated protein kinase 7;PRKM7." in publications.

  5. What is the shipping cost for "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MAPK7 Antibody (Phospho-Ser731/Thr733) (OABF01574)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MAPK7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MAPK7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MAPK7"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MAPK7"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MAPK7"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MAPK7"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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