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Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)
Datasheets/Manuals | Printable datasheet for OAAQ00003 |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Mouse, Rat |
Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
Clonality | Monoclonal |
Clone | ERK12T202Y204-A11 |
Isotype | Rabbit IgG1k |
Host | Rabbit |
Conjugation | APC: Allophycocyanin |
Application | FC |
Reconstitution and Storage | 2-8C |
Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr202/Tyr204 of human phospho Erk1/2. |
Purification | Protein A+G |
Target Post-Translational Modification | Phospho-Thr202/Tyr204 |
Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
Reference | Roskoski Jr R. (2012) Pharmacological Research. 66: 105-143. |
Gene Symbol | MAPK3, MAPK1 |
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Gene Full Name | mitogen-activated protein kinase 3, mitogen-activated protein kinase 1 |
Alias Symbols | ERK1, ERT2, ERK-1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, p44-ERK1, p44-MAPK |
NCBI Gene Id | 5595; 5594 |
Protein Name | mitogen-activated protein kinase 3, mitogen-activated protein kinase 1 |
Description of Target | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
Uniprot ID | P27361, P28482 |
Protein Accession # | NP_001035145.1 |
Nucleotide Accession # | NM_001040056.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)" provided in?
This item is provided in "Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)"?
This target may also be called "ERK1, ERT2, ERK-1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, p44-ERK1, p44-MAPK" in publications.
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What is the shipping cost for "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human MAPK3/MAPK1 Antibody : APC (Phospho-Thr202/Tyr204) (OAAQ00003)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MAPK3, MAPK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MAPK3, MAPK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MAPK3, MAPK1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MAPK3, MAPK1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MAPK3, MAPK1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MAPK3, MAPK1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.