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MAP4K5 Antibody (OAGA00757)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ICC, IF, IHC-FFPE, WB
Additional Information:
Background: This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
:::
Positive Controls: 293T, A431, H1299, HepG2, Molt-4, Raji
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Cellular Localization: Cytoplasm
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-7256 from Santa Cruz Biotechnology.
Immunogen:
Synthetic peptide contain a sequence corresponding to a region within amino acids 417 and 482 of KHS
Purification:
Purified by antigen-affinity chromatography.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-MAP4K5 antibody - OAGA00757
Application Info:
Suggested starting dilutions are as follows: WB: 1:1000-1:10000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol:
MAP4K5
Official Gene Full Name:
Mitogen-activated protein kinase kinase kinase kinase 5
Alias Symbols:
GCKR antibody, KHS antibody, KHS1 antibody, MAPKKKK5 antibody, MAP4K5 antibody, MEK kinase kinase 5 antibody, kinase homologous to SPS1/STE20 antibody, MEKKK 5 antibody, MAPK/ERK kinase kinase kinase 5 antibody, germinal center kinase-related antibody, mi
NCBI Gene Id:
11183
Protein Name:
Mitogen-activated protein kinase kinase kinase kinase 5
Swissprot Id:
Q9Y4K4
Protein Accession #:
NP_006566.2
Molecular Weight:
95 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAP4K5.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAP4K5.

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