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Catalog No: OAAB06460
Size:400ul
Price: $438.00
SKU
OAAB06460
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-MAP4K3 antibody - OAAB06460
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeRabbit Ig
HostRabbit
ApplicationFC, IHC-P, WB
Additional InformationFunction: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Tissue Location: Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis MAP4K3 antibody is generated from rabbits immunized with a recombinant protein of human MAP4K3.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Intended UseFor research use only and not for use in diagnostic or therapeutic procedures.
Application InfoWB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Other Applications Image 1 DataMAP4K3 Antibody flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Gene SymbolMAP4K3
Alias SymbolsGLK, MEKKK3, MEKKK 3, MAPKKKK3, RAB8IPL1
NCBI Gene Id8491
Protein NameMitogen-activated protein kinase kinase kinase kinase 3
Description of TargetMAP4K3 encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).
Uniprot IDQ8IVH8
Protein Accession #NP_001257354.1
Molecular Weight101 kDa
  1. What is the species homology for "MAP4K3 Antibody (OAAB06460)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "MAP4K3 Antibody (OAAB06460)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "MAP4K3 Antibody (OAAB06460)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MAP4K3 Antibody (OAAB06460)"?

    This target may also be called "GLK, MEKKK3, MEKKK 3, MAPKKKK3, RAB8IPL1" in publications.

  5. What is the shipping cost for "MAP4K3 Antibody (OAAB06460)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MAP4K3 Antibody (OAAB06460)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MAP4K3 Antibody (OAAB06460)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "101 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MAP4K3 Antibody (OAAB06460)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MAP4K3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MAP4K3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MAP4K3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MAP4K3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MAP4K3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MAP4K3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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