MAP3K9 Antibody (Phospho-Thr312) (OABF01750)

Catalog No: OABF01750

Size:100UL

Product Info

• Predicted Species Reactivity: Bovine|Chicken|Dog|Horse|Human|Mouse|Porcine|Rabbit|Rat
• Product Format: Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
  Modification: Phosphorylation (Thr312)
• Reconstitution and Storage: -20°C
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human MAP3K9 around the phosphorylation site of Thr312
• Purification: Protein A Purified
• Concentration: 1 ug/ul
• Application Info: IHC-P: 1:100-500
  Fluorescent-IHC: 1:50-200

Target Info

• Gene Symbol: MAP3K9
• Gene Full Name: mitogen-activated protein kinase kinase kinase 9
• Alias Symbols: MEKK9;mitogen-activated protein kinase kinase kinase 9;Mixed lineage kinase 1;mixed lineage kinase 1 (tyr and ser/thr specificity);MLK1;PRKE1.
• NCBI Gene Id: 4293
• Protein Name: Mitogen-activated protein kinase kinase kinase 9
• Description of Target: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
• Uniprot ID: P80192