Catalog No: ARP32402_P050-HRP
Size:100ul
Price: $434.00
SKU
ARP32402_P050-HRP
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MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-TAB2 (ARP32402_P050-HRP) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationIHC, WB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K7IP2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: QKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDLNFSDDSG
Concentration0.5 mg/ml
Blocking PeptideFor anti-TAB2 (ARP32402_P050-HRP) antibody is Catalog # AAP32402 (Previous Catalog # AAPP03393)
Sample Type Confirmation

TAB2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

ReferenceKanayama, A., et al., ,(2004) Mol. Cell 15 (4), 535-548
Publications

Thienpont, B. et al. Haploinsufficiency of TAB2 causes congenital heart defects in humans. Am. J. Hum. Genet. 86, 839-49 (2010). WB, IHC, Human, Mouse, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Rat 20493459

Gene SymbolTAB2
Gene Full NameTGF-beta activated kinase 1/MAP3K7 binding protein 2
Alias SymbolsCHTD2, TAB-2, MAP3K7IP2
NCBI Gene Id23118
Protein NameTGF-beta-activated kinase 1 and MAP3K7-binding protein 2
Description of TargetMAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Uniprot IDQ9NYJ8
Protein Accession #NP_055908
Nucleotide Accession #NM_015093
Protein Size (# AA)693
Molecular Weight76kDa
Protein InteractionsUBC; PIAS3; UBE2I; TRAF6; SUMO2; IRAK1; MAP3K7; TRIM38; SIK1; SIK3; TRIM22; NPM1; CST9L; SLC19A3; env; TAB1; NUMBL; IKBKG; FOSL1; ZBTB16; YWHAZ; VIM; TGM2; PPP2CB; IKBKB; GTF2I; FN1; HSP90AA1; BST2; MALT1; WDR34; APP; ESR1; MAP3K8; AR; TRIM5; TBL1XR1; MBD
  1. What is the species homology for "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)"?

    This target may also be called "CHTD2, TAB-2, MAP3K7IP2" in publications.

  5. What is the shipping cost for "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "76kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MAP3K7IP2 Antibody - N-terminal region : HRP (ARP32402_P050-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TAB2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TAB2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TAB2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TAB2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TAB2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TAB2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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