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MAP2K4 Antibody - C-terminal region : HRP (ARP30544_T100-HRP)

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100 ul
$249.00
In Stock

Conjugation Options

ARP30544_T100 Unconjugated

ARP30544_T100-FITC Conjugated

ARP30544_T100-Biotin Conjugated

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Gene Symbol:
MAP2K4
NCBI Gene Id:
6416
Swissprot Id:
P45985
Protein Accession #:
NP_003001
Nucleotide Accession #:
NM_003010
Alias Symbols:
JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1
Description of Target:
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Protein Size (# AA):
399
Molecular Weight:
44kDa
Host:
Rabbit
Clonality:
Polyclonal
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAP2K4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAP2K4.
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAP2K4
Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: NLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMA
Product Format:
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
0.6-0.7 mg/ml
Protein Interactions:
UBC; EGFR; GEMIN5; MAP3K5; MAP3K1; GCH1; MAPK10; MAPK9; MAPK8; MAPK1; ARRB2; ARRB1; MAP3K7; RBBP8; JUN; MAP2K7; APP; MAP3K2; MAPK14; AKT1; LRRK2; MAP2K4; MAP2K6; MAP3K4; MAP3K3; PML; BLNK; ITCH; MAPK8IP3; ZAK; SPAG9; TRIB1; MAP3K14; CFLAR; MAPK12; EFNA4;
Blocking Peptide:
For anti-MAP2K4 (ARP30544_T100-HRP) antibody is Catalog # AAP30544
Datasheets/Manuals:
Printable datasheet for anti-MAP2K4 (ARP30544_T100-HRP) antibody
Conjugation:
HRP

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