Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: OAGA08491
Size:100 ul
Price: $372.00
SKU
OAGA08491
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for OAGA08491
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityMonoclonal
CloneGT1162
IsotypeIgG2b
HostMouse
ApplicationWB
Reconstitution and StorageKeep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
ImmunogenRecombinant protein encompassing a sequence within the center region of human MEK2. The exact sequence is proprietary.
PurificationAffinity purified by Protein G.
Concentration1 mg/ml
Application InfoSuggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage BufferPBS
Gene SymbolMAP2K2
Gene Full Namemitogen-activated protein kinase kinase 2
Alias SymbolsCFC4, MEK2, MKK2, MAPKK2, PRKMK2
NCBI Gene Id5605
Protein Namedual specificity mitogen-activated protein kinase kinase 2
Description of TargetThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
Uniprot IDP36507
Protein Accession #NP_109587.1
Nucleotide Accession #NM_030662.3
  1. What is the species homology for "MAP2K2 Antibody (OAGA08491)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "MAP2K2 Antibody (OAGA08491)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "MAP2K2 Antibody (OAGA08491)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MAP2K2 Antibody (OAGA08491)"?

    This target may also be called "CFC4, MEK2, MKK2, MAPKK2, PRKMK2" in publications.

  5. What is the shipping cost for "MAP2K2 Antibody (OAGA08491)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MAP2K2 Antibody (OAGA08491)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MAP2K2 Antibody (OAGA08491)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MAP2K2 Antibody (OAGA08491)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MAP2K2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MAP2K2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MAP2K2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MAP2K2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MAP2K2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MAP2K2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:MAP2K2 Antibody (OAGA08491)
Your Rating
We found other products you might like!