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Catalog No: OAAB16522
Size:400ul
Price: $438.00
SKU
OAAB16522
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB16522
Product Info
Predicted Species ReactivityHuman, Pig
Product FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB, IHC
Additional InformationPrecautions: MAGED1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
::Function: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex
::Cellular Location: Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein (By similarity). Note=Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF (By similarity)
Tissue Location: Expressed in bone marrow stromal cells from both multiple myeloma patients and healthy donors. Seems to be ubiquitously expressed
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis MAGED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-456 amino acids from the Central region of human MAGED1.
Predicted Homology Based on Immunogen SequenceHuman; Pig
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Application InfoWB: 1:1000
IHC-P: 1:50~100
Gene SymbolMAGED1
Alias SymbolsNRAGE, DLXIN-1
NCBI Gene Id9500
Protein NameMelanoma-associated antigen D1
Description of TargetPurified Rabbit Polyclonal Antibody (Pab)
Uniprot IDQ9Y5V3
Protein Accession #NP_001005332.1
Molecular Weight86161 Da
  1. What is the species homology for "MAGED1 Antibody - middle region (OAAB16522)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Pig".

  2. How long will it take to receive "MAGED1 Antibody - middle region (OAAB16522)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "MAGED1 Antibody - middle region (OAAB16522)" provided in?

    This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MAGED1 Antibody - middle region (OAAB16522)"?

    This target may also be called "NRAGE, DLXIN-1" in publications.

  5. What is the shipping cost for "MAGED1 Antibody - middle region (OAAB16522)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MAGED1 Antibody - middle region (OAAB16522)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MAGED1 Antibody - middle region (OAAB16522)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "86161 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MAGED1 Antibody - middle region (OAAB16522)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MAGED1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MAGED1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MAGED1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MAGED1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MAGED1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MAGED1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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