MAGEA1 Antibody - middle region (OAAB16512)

Catalog No: OAAB16512

Size:400ul

Western blot analysis of anti-MAGEA1 Antibody (Center) in Hela cell line lysates (35ug/lane). MAGEA1(arrow) was detected using the purified Pab (1:60dilution).

MAGEA1 is strongly supported by BioGPS gene expression data to be expressed in Hela

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MAGEA1 Antibody (Center) (Cat.# OAAB16512), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: MAGEA1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1 May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes
  Cellular Location: Cytoplasm. Nucleus.
  Tissue Location: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This MAGEA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-173 amino acids from the Central region of human MAGEA1.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  MAGEA1 is strongly supported by BioGPS gene expression data to be expressed in Hela

• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: MAGEA1
• Alias Symbols: CT1.1, MAGE1
• NCBI Gene Id: 4100
• Protein Name: Melanoma-associated antigen 1
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P43355
• Protein Accession #: NP_004979.3
• Molecular Weight: 34342 Da