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Catalog No: ARP47760_P050
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ARP47760_P050
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Datasheets/ManualsPrintable datasheet for anti-MAFA (ARP47760_P050) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human MAFA
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 79%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 83%
Peptide SequenceSynthetic peptide located within the following region: KPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAA
Concentration0.5 mg/ml
Blocking PeptideFor anti-MAFA (ARP47760_P050) antibody is Catalog # AAP47760 (Previous Catalog # AAPS22512)
ReferenceMatsuoka,T.A., (2007) Mol. Endocrinol. 21 (11), 2764-2774
Publications

Molecular and genetic regulation of pig pancreatic islet cell development. Development. 147, NULL (2020). 32108026

Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes. Mol Metab. 54, 101330 (2021). 34500108

Description
Gene SymbolMAFA
Gene Full NameV-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
Alias SymbolsINSDM, hMafA, RIPE3b1
NCBI Gene Id389692
Protein NameTranscription factor MafA
Description of TargetMAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS).MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1062 AC105118.23 99326-100387 c
Uniprot IDQ8NHW3
Protein Accession #NP_963883
Nucleotide Accession #NM_201589
Protein Size (# AA)353
Molecular Weight37kDa
Protein InteractionsMapk14; UBC; SUMO1; NEUROD1; PDX1; MAF; MAPK1;
  1. What is the species homology for "MAFA Antibody - N-terminal region (ARP47760_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Zebrafish".

  2. How long will it take to receive "MAFA Antibody - N-terminal region (ARP47760_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MAFA Antibody - N-terminal region (ARP47760_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MAFA Antibody - N-terminal region (ARP47760_P050)"?

    This target may also be called "INSDM, hMafA, RIPE3b1" in publications.

  5. What is the shipping cost for "MAFA Antibody - N-terminal region (ARP47760_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MAFA Antibody - N-terminal region (ARP47760_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MAFA Antibody - N-terminal region (ARP47760_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MAFA Antibody - N-terminal region (ARP47760_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MAFA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MAFA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MAFA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MAFA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MAFA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MAFA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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