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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for MAD2L1 Antibody (OACA07850) (OACA07850) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Mitotic spindle assembly checkpoint protein MAD2A protein (1-205AA) |
Purification | Affinity Purified |
Preservative | 0.02% sodium azide |
Formulation | PBS with, 50% glycerol, pH7.3. |
Reference | [1]Insights into Mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric Mad2 dimer."Yang M., Li B., Liu C.-J., Tomchick D.R., Machius M., Rizo J., Yu H., Luo X.PLoS Biol. 6:E50-E50(2008). [2]p31comet blocks Mad2 activation through structural mimicry."Yang M., Li B., Tomchick D.R., Machius M., Rizo J., Yu H., Luo X.Cell 131:744-755(2007). [3]The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint." Mapelli M., Massimiliano L., Santaguida S., Musacchio A. Cell 131:730-743(2007). |
Gene Symbol | MAD2L1 |
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Gene Full Name | mitotic arrest deficient 2 like 1 |
Alias Symbols | HSMAD2;MAD2;MAD2 (mitotic arrest deficient, yeast, homolog)-like 1;MAD2 mitotic arrest deficient-like 1;MAD2-like protein 1;mitotic arrest deficient 2-like protein 1;mitotic arrest deficient, yeast, homolog-like 1;mitotic spindle assembly checkpoint protein MAD2A. |
NCBI Gene Id | 4085 |
Protein Name | Mitotic spindle assembly checkpoint protein MAD2A |
Description of Target | Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. |
Uniprot ID | Q13257 |
Protein Accession # | NP_002349 |
Nucleotide Accession # | NM_002358 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MAD2L1 Antibody (OACA07850)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "MAD2L1 Antibody (OACA07850)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "MAD2L1 Antibody (OACA07850)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MAD2L1 Antibody (OACA07850)"?
This target may also be called "HSMAD2;MAD2;MAD2 (mitotic arrest deficient, yeast, homolog)-like 1;MAD2 mitotic arrest deficient-like 1;MAD2-like protein 1;mitotic arrest deficient 2-like protein 1;mitotic arrest deficient, yeast, homolog-like 1;mitotic spindle assembly checkpoint protein MAD2A." in publications.
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What is the shipping cost for "MAD2L1 Antibody (OACA07850)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MAD2L1 Antibody (OACA07850)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MAD2L1 Antibody (OACA07850)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MAD2L1 Antibody (OACA07850)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MAD2L1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MAD2L1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MAD2L1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MAD2L1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MAD2L1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MAD2L1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.