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LY6G Antibody (OATA00269)
| Datasheets/Manuals | Printable datasheet for OATA00269 |
|---|
| Predicted Species Reactivity | Mouse |
|---|---|
| Product Format | Liquid 10mM NaH2PO4, 150mM NaCl (pH 7.2) |
| Clonality | Monoclonal |
| Clone | 1A8 |
| Isotype | Rat IgG2a, kappa |
| Host | Rat |
| Application | FC, FN, IHC-F, IHC-P, IP |
| Additional Information | Endotoxin: Less than or equal to 0.01 EU/ug, as determined by LAL assay |
| Reconstitution and Storage | It is recommended to store the product undiluted at 4°C. Do not freeze. Stable for 12 months from date of receipt. |
| Purification | Purified from tissue culture supernatant via affinity chromatography. |
| Concentration | 2.0 mg/ml |
| Specificity | Ly-6G |
| Application Info | Antibodies are tested by flow cytometry. |
| Reference | Kamaly N, Fredman G, Subramanian M, Gadde S, Pesic A, Cheung L, Fayad ZA, Langer R, Tabas I and Cameron O. 2013. Proc. Natl. Acad. Sci. 110. 6506-6511. (flow cytometry). Stinn W, Buettner A, Weiler H, Friedrichs B, Luetjen S, van Overveld F, Meurrens K, Janssens K, Gebel S, Stabbert R and Haussman H-J. 2013. Toxicol. Sci. 131: 596-611 (flow cytometry). Enoksson M, Moller-Westerberg C, Wicher G, Fallon PG, Forsberg-Nilsson K, Lunderius-Andersson C and Nilsson G. 2013. Blood. 121. 530-536 (flow cytometry). |
| Gene Symbol | LY6G |
|---|---|
| Gene Full Name | lymphocyte antigen 6 complex, locus G |
| Alias Symbols | Gr, Gr-, Gr1, Gr-1, Ly-6, Ly-6G |
| NCBI Gene Id | 546644 |
| Protein Name | lymphocyte antigen 6G |
| Description of Target | The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "LY6G Antibody (OATA00269)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".
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How long will it take to receive "LY6G Antibody (OATA00269)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "LY6G Antibody (OATA00269)" provided in?
This item is provided in "Liquid 10mM NaH2PO4, 150mM NaCl (pH 7.2)".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "LY6G Antibody (OATA00269)"?
This target may also be called "Gr, Gr-, Gr1, Gr-1, Ly-6, Ly-6G" in publications.
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What is the shipping cost for "LY6G Antibody (OATA00269)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "LY6G Antibody (OATA00269)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "LY6G Antibody (OATA00269)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "LY6G Antibody (OATA00269)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "LY6G"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "LY6G"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "LY6G"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "LY6G"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "LY6G"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "LY6G"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
