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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for anti-LTC4S (OAED00035) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat |
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Clonality | Monoclonal |
Clone | 6E7 |
Isotype | IgG |
Host | Mouse |
Application | RIA |
Reconstitution and Storage | Long Term Storage : -20C |
Immunogen | Leukotriene C4 |
Concentration | 1.0mg/ml |
Specificity | Recognizes human, mouse and rat LTC4. |
Source | Purified from concentrated hybridoma tissue culture supernatant. |
Formulation | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
Purity | Protein G-affinity purified. |
Application Info | ELISA Radioimmunoassay (1:1000) Optimal conditions must be determined individually for each application. |
Reference | International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors: C. Brink, et al.; Pharmacol. Rev. 55, 195 (2003), Abstract; Leukotriene B4: metabolism and signal transduction: T. Yokomizo, et al.; Arch. Biochem. Biophys. 385, 231 (2001), Abstract; |
Gene Symbol | LTC4S |
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Gene Full Name | Leukotriene C4 synthase |
NCBI Gene Id | 4056 |
Protein Name | Leukotriene C4 synthase |
Description of Target | Leukotrienes are metabolic products of arachidonic acid formed by the action of 5-lipoxygenase (5-LO), with the principal products being leukotrienes C4 (LTC4) and B4 (LTB4). Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability. |
Uniprot ID | Q16873 |
Protein Accession # | NP_665874.1 |
Nucleotide Accession # | NM_145867.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "LTC4S Antibody (OAED00035)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "LTC4S Antibody (OAED00035)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
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What buffer format is "LTC4S Antibody (OAED00035)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "LTC4S Antibody (OAED00035)"?
This target may also be called "" in publications.
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What is the shipping cost for "LTC4S Antibody (OAED00035)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "LTC4S Antibody (OAED00035)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "LTC4S Antibody (OAED00035)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "LTC4S Antibody (OAED00035)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "LTC4S"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "LTC4S"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "LTC4S"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "LTC4S"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "LTC4S"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "LTC4S"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.