LTB Antibody - C-terminal region (OASG04291)

Catalog No: OASG04291

Size:100 uL

Western Blot using HepG2

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. In PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ELISA, IF, WB
• Reconstitution and Storage: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
• Immunogen: The antiserum was produced against synthesized peptide derived from the human TNFC at the amino acid range 181-230
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: Varies by lot. Please see vial.
• Specificity: LT-Beta Polyclonal Antibody detects endogenous levels of LT-Beta protein.
• Application Info: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000;

Target Info

• Gene Symbol: LTB
• Gene Full Name: lymphotoxin beta (TNF superfamily, member 3)
• Alias Symbols: p33, TNFC, TNFSF3, TNLG1C
• NCBI Gene Id: 4050; 16994;
• Description of Target: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Uniprot ID: Q06643, P41155
• Molecular Weight: 22 kDa