LRRFIP2 Antibody (OAGA06649)

Catalog No: OAGA06649

Size:100 ul

LRRFIP2 antibody detects LRRFIP2 protein at cytosol on mouse muscle by immunohistochemical analysis.
Sample: Paraffin-embedded mouse muscle.
LRRFIP2 antibody dilution: 1:500.

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-P
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LRRFIP2. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.66 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: LRRFIP2
• Gene Full Name: LRR binding FLII interacting protein 2
• Alias Symbols: HUFI-2
• NCBI Gene Id: 9209
• Protein Name: leucine-rich repeat flightless-interacting protein 2
• Description of Target: The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.
• Uniprot ID: Q9Y608
• Protein Accession #: NP_001127841.1
• Nucleotide Accession #: NM_001134369.2