LRRFIP1 Recombinant Protein (OPCD05039)

Catalog No: OPCD05039

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Glu128-Asn250
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: LRRFIP1
• Gene Full Name: LRR binding FLII interacting protein 1
• Alias Symbols: FLAP1;FLAP-1;FLIIAP1;GC-binding factor 2;GCF2;GCF-2;HUFI-1;leucine rich repeat (in FLII) interacting protein 1;leucine-rich repeat flightless-interacting protein 1;LRR FLII-interacting protein 1;NEDD8-conjugating enzyme;TAR RNA-interacting protein;TRIP.
• NCBI Gene Id: 9208
• Protein Name: Leucine-rich repeat flightless-interacting protein 1
• Description of Target: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
• Uniprot ID: Q32MZ4
• Protein Accession #: NP_001131022.1
• Nucleotide Accession #: NM_001137550.1
• Protein Size (# AA): Glu128~Asn250
• Molecular Weight: 17kDa