LRPPRC Antibody - N-terminal region : FITC (ARP41093_P050-FITC)

Catalog No: ARP41093_P050-FITC

Size:100ul

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Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LPPRC
• Purification: Affinity purified
• Predicted Homology Based on Immunogen Sequence: Cow: 79%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
• Peptide Sequence: Synthetic peptide located within the following region: NEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYCNVGDIEGASKILGFMK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-LRPPRC (ARP41093_P050-FITC) antibody is Catalog # AAP41093
• Reference: N/A

Target Info

• Gene Symbol: LRPPRC
• Gene Full Name: leucine rich pentatricopeptide repeat containing
• Alias Symbols: LSFC, GP130, LRP130, MC4DN5, CLONE-23970
• NCBI Gene Id: 10128
• Protein Name: leucine-rich PPR motif-containing protein, mitochondrial
• Description of Target: This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.
• Uniprot ID: P42704
• Protein Accession #: NP_573566
• Protein Size (# AA): 1394
• Molecular Weight: 153kDa
• Protein Interactions: SPRTN; CEP76; HAUS2; CEP250; SART3; AURKB; TP53; AURKA; SUMO2; SUMO3; CDKN1A; IVNS1ABP; STAU1; UBC; MDM2; LGR4; ASB5; RNF2; EZH2; BMI1; PARK2; FBXO6; ADRB2; METTL22; vpu; ITGA4; FN1; C1QBP; VCAM1; PEX14; SMURF1; ILF3; CPS1; MRPS35; SEC23A; GRK5; UBD; CDK2