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Catalog No: OPCD05024
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OPCD05024
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Datasheets/ManualsPrintable datasheet for LRP1 Recombinant Protein (OPCD05024)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Lys337-Ala426
Subcellular Location: Membrane, Chromosome
Predicted isoelectric point: 6.4
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 97%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolLrp1
Gene Full Namelow density lipoprotein receptor-related protein 1
Alias SymbolsA2;A2mr;AI316852;alpha 2-macroglobulin receptor;Alpha-2-macroglobulin receptor;b2b1554C;b2b1554Clo;CD91;lipoprotein receptor-related protein;Lrp;LRP-1;prolow-density lipoprotein receptor-related protein 1.
NCBI Gene Id16971
Protein NameProlow-density lipoprotein receptor-related protein 1
Description of TargetEndocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development (PubMed:1423604). Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Acts as an alpha-2-macroglobulin receptor (By similarity).
Uniprot IDQ91ZX7
Protein Accession #NP_032538.2
Nucleotide Accession #NM_008512.2
Protein Size (# AA)Lys337~Ala426
Molecular Weight41kDa
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