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LRP1 Antibody (OASA02538)

0.1 mg
$369.00
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Gene Symbol:
LRP1
NCBI Gene Id:
4035
Protein Name:
Prolow-density lipoprotein receptor-related protein 1
Swissprot Id:
Q07954
Protein Accession #:
NP_002323.2
Alias Symbols:
APR, LRP, A2MR, CD91, APOER, TGFBR5, IGFBP3R, FLJ16451, MGC88725, LRP1
Replacement Item:
This antibody may replace item sc-16166 from Santa Cruz Biotechnology.
Description of Target:
MOUSE ANTI HUMAN CD91
Protein Size (# AA):
4544
Host:
Mouse
Clonality:
Monoclonal
Application:
IHC-AFF, ELISA, FC, IP, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express LRP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express LRP1.
Immunogen:
The immunogen for anti-LRP1 antibody: purified CD91
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Datasheets/Manuals:
Printable datasheet for anti-LRP1 antibody - OASA02538
Specificity:
CD91
Clone:
A2Mr alpha-2
Isotype:
IgG1
Application Info:
Flow Cytometry:    1/50 1/100
ELISA:    Direct
Western Blotting:    Non-reducing conditions
Additional Information:
Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the NS1 mouse myeloma cell line.
Histology Positive Control Tissue: Liver
:::
Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preservative Stabilisers: 0.09% - Sodium Azide
:::
Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline pH7.4
Target Reference:
1. Moestrup, S.K. et al. (1992) Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues. Cell Tissue Res. 269: 375-382.
2. Moestrup, S.K. and Hokland, P. (1992) Surface expression of the alpha 2-macroglobulin receptor on human malignant blood cells. Leuk. Res. 16: 227-234.
3. Chen, J.S. et al. (2010) Secreted Heat Shock Protein 90{alpha} Induces Colorectal Cancer Cell Invasion through CD91/LRP-1 and NF-{kappa}B-mediated Integrin {alpha}V Expression. J Biol Chem. 285: 25458-66.

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