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Catalog No: OPCD05003
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OPCD05003
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Datasheets/ManualsPrintable datasheet for LPCAT1 Recombinant Protein (OPCD05003)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Pro70-Arg237
Subcellular Location: Membrane, Golgi apparatus
Isoelectric Point: 10.1
Reconstitution and Storage2°C to 8°C|-80°C
Concentration300 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolLPCAT1
Gene Full Namelysophosphatidylcholine acyltransferase 1
Alias Symbols1-acylglycerol-3-phosphate O-acyltransferase;1-acylglycerophosphocholine O-acyltransferase;1-alkenylglycerophosphocholine O-acyltransferase;1-alkylglycerophosphocholine O-acetyltransferase;acetyl-CoA:lyso-PAF acetyltransferase;acetyl-CoA:lyso-platelet-activating factor acetyltransferase;acyltransferase-like 2;AGPAT10;AGPAT9;AYTL2;LPC acyltransferase 1;lpcat;LPCAT-1;lyso-PAF acetyltransferase;lysoPAFAT;lysoPC acyltransferase 1;lysophosphatidylcholine acyltransferase 1;PFAAP3;phosphonoformate immuno-associated protein 3.
NCBI Gene Id79888
Protein NameLysophosphatidylcholine acyltransferase 1
Description of TargetPossesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505). Activity is calcium-independent (By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16864775). Involved in the regulation of lipid droplet number and size (PubMed:25491198).
Uniprot IDQ8NF37
Protein Accession #NP_079106.3
Nucleotide Accession #NM_024830.3
Protein Size (# AA)Pro70~Arg237
Molecular Weight49kDa
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