LPA Antibody (OAAD00290)

Catalog No: OAAD00290

Size:0.1ml

western blot analysis using LPA mouse mAb against truncated LPA-His recombinant protein (1) and truncated Trx-LPA(aa4330-4521) recombinant protein (2).

Immunohistochemical analysis of paraffin-embedded human Liver tissues using LPA mouse mAb

Product Info

• Predicted Species Reactivity: Human
• Clonality: Monoclonal
• Clone: 8F6A9, 8H5C5
• Isotype: IgG1
• Host: Mouse
• Application: WB, IHC
• Reconstitution and Storage: Store at 4C, for long term storage, store at -20C.
• Immunogen: Purified recombinant fragment of LPA (4330-4521) expressed in E. Coli.
• Formulation: Ascitic fluid containing 0.03% sodium azide.
• Application Info: Western Bloting: 1/500 - 1/2000.
  Immunohistochemistry: 1/200 - 1/1000.
  ELISA: Propose dilution 1/10000.
  Not yet tested in other applications.
  Determining optimal working dilutions by titration test.
• Reference: 1. J Stroke Cerebrovasc Dis. 2007 Sep-Oct;16(5):220-4.
  2. Clin Chim Acta. 2008 Jan;387(1-2):109-12.

Target Info

• Alias Symbols: LP, AK38, APOA
• NCBI Gene Id: 4018
• Description of Target: LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.
• Uniprot ID: P08519