LMO2 Antibody - N-terminal region (P100952_P050)

Catalog No: P100952_P050

WB Suggested Anti-LMO2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human kidney

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Mouse, Rat, Dog, Guinea Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LMO2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Dog: 100%; Guinea Pig: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: GGGARAPEGVRAPAAGQPRATKGAPPPPGTPPPSPMSSAIERKSLDPSEE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-LMO2 (P100952_P050) antibody is Catalog # AAP31307 (Previous Catalog # AAPP02056)
• Reference: Yuan,W., (2008) Leukemia 22 (5), 1067-1071
• Description:
  View product citations for LMO2 Antibody - N-terminal region (P100952_P050)on CiteAb

Target Info

• Gene Symbol: LMO2
• Gene Full Name: LIM domain only 2 (rhombotin-like 1)
• Alias Symbols: TTG2, LMO-2, RBTN2, RHOM2, RBTNL1
• NCBI Gene Id: 4005
• Protein Name: Rhombotin-2
• Description of Target: LMO2 acts with TAL1/SCL to regulate red blood cell development. LMO2 also acts with LDB1 to maintain erythroid precursors in an immature state.LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P25791
• Protein Accession #: NP_005565
• Nucleotide Accession #: NM_005574
• Protein Size (# AA): 158
• Molecular Weight: 18kDa
• Protein Interactions: ADAMTSL4; MBIP; HOOK1; TFPT; NOTCH2NL; KRTAP10-7; CCDC36; NUTM1; SPERT; FAM154A; CLHC1; KRT40; SSX2IP; CMTM5; MRFAP1L1; IFT43; C1orf94; LZTS2; TSC22D4; DBF4B; CCDC33; RINT1; NIF3L1; TRIM54; AGTRAP; ZFP64; BANP; STAT3; STAT1; SOX5; SKP1; ROCK1; REL; PRKG1;