LLGL1 Antibody - N-terminal region (OAAB15829)

Catalog No: OAAB15829

Size:400ul

Western blot analysis of anti-hLLGL1 Pab (Cat. # OAAB15829) in 293 cell line lysate. hLLGL1(arrow) was detected using the purified Pab.

LLGL1 is supported by BioGPS gene expression data to be expressed in HEK293

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Precautions: LLGL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane
  Cellular Location: Early endosome membrane (By similarity). Golgi apparatus, trans-Golgi network membrane (By similarity) Golgi apparatus membrane (By similarity). Cell projection, axon (By similarity). Cytoplasm, cytoskeleton. Note=Localized to the lateral membrane during the polarization and formation cell-cell contacts. Enriched in developping axons (By similarity)
  Tissue Location: Expressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This LLGL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-205 amino acids from the N-terminal region of human LLGL1.
• Predicted Homology Based on Immunogen Sequence: Cow; Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  LLGL1 is supported by BioGPS gene expression data to be expressed in HEK293

• Application Info: WB: 1:1000

Target Info

• Gene Symbol: LLGL1
• Alias Symbols: DLG4, HUGL, LLGL, Lgl1, Mgl1, HUGL1, HUGL-1
• NCBI Gene Id: 3996
• Protein Name: Lethal(2) giant larvae protein homolog 1
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q15334
• Protein Accession #: NP_004131.3
• Molecular Weight: 115418 Da