LITAF Antibody (OAGA00745)

Catalog No: OAGA00745

Size:100 ul

Sample (30 ug of whole cell lysate)
A: Hep G2
12% SDS PAGE
OAGA00745 diluted at 1:1000

LITAF antibody [N1C3] detects LITAF protein at cytoplasm on placenta by immunohistochemical analysis.
Sample: Paraffin-embedded placenta.
LITAF antibody [N1C3] (OAGA00745) dilution: 1:100.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC, WB
• Additional Information: Background: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
  Positive Controls: HeLa, HepG2
  Cellular Localization: Lysosome membrane; Peripheral membrane protein; Cytoplasmic side
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 161 of LITAF (Uniprot ID#Q99732)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: LITAF
• Gene Full Name: Lipopolysaccharide-induced tumor necrosis factor-alpha factor
• Alias Symbols: PIG7, SIMPLE, TP53I7
• NCBI Gene Id: 9516
• Protein Name: Lipopolysaccharide-induced tumor necrosis factor-alpha factor
• Uniprot ID: Q99732
• Protein Accession #: NP_001129944.1
• Molecular Weight: 17 kDa