LIFR Antibody - middle region (OASG04241)

Catalog No: OASG04241

Size:100 uL

Western Blot using 293

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human LIFR. Location: 390-470aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: LIFR Polyclonal Antibody detects endogenous levels of LIFR protein.
• Application Info: WB 1:500-1:2000; ELISA 1:10000;

Target Info

• Gene Symbol: LIFR
• Gene Full Name: leukemia inhibitory factor receptor alpha
• Alias Symbols: SWS, SJS2, STWS, CD118, LIF-R
• NCBI Gene Id: 3977;
• Description of Target: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.
• Uniprot ID: P42702