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Catalog No: ARP44923_P050
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ARP44923_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-LFNG (ARP44923_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Guinea Pig, Horse, Yeast
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human LFNG
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 100%
Peptide SequenceSynthetic peptide located within the following region: LSEYFSLLTRARRDAGPPPGAAPRPADGHPRPLAEPLAPRDVFIAVKTTK
Concentration0.5 mg/ml
Blocking PeptideFor anti-LFNG (ARP44923_P050) antibody is Catalog # AAP44923 (Previous Catalog # AAPP26005)
ReferenceSparrow,D.B., (2006) Am. J. Hum. Genet. 78 (1), 28-37
Gene SymbolLFNG
Gene Full NameLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Alias SymbolsSCDO3
NCBI Gene Id3955
Protein Namebeta-1,3-N-acetylglucosaminyltransferase lunatic fringe
Description of TargetThis gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3.
Uniprot IDQ8NES3-3
Protein Accession #NP_001035258
Nucleotide Accession #NM_001040168
Protein Size (# AA)361
Molecular Weight39kDa
Protein InteractionsAPP; NOTCH2; NOTCH1;
  1. What is the species homology for "LFNG Antibody - N-terminal region (ARP44923_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Guinea Pig, Horse, Yeast".

  2. How long will it take to receive "LFNG Antibody - N-terminal region (ARP44923_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "LFNG Antibody - N-terminal region (ARP44923_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "LFNG Antibody - N-terminal region (ARP44923_P050)"?

    This target may also be called "SCDO3" in publications.

  5. What is the shipping cost for "LFNG Antibody - N-terminal region (ARP44923_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "LFNG Antibody - N-terminal region (ARP44923_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "LFNG Antibody - N-terminal region (ARP44923_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "39kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "LFNG Antibody - N-terminal region (ARP44923_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "LFNG"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "LFNG"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "LFNG"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "LFNG"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "LFNG"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "LFNG"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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