Size:200ug
$219.00
Discontinued
SKU
APL10567
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LEF1 Protein Lysate (APL10567)

Catalog#: APL10567
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Reconstitution and Storage Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Quality Control This product was tested on western blot.
Application : Western blot standard.
Observed Molecular Weight: 39
Expression system : Bacteria
Tag GST in N-terminal
Datasheets/Manuals Printable datasheet for anti-LEF1 (APL10567) antibody
Gene Symbol LEF1
Alias Symbols TCF10, TCF7L3, FLJ46390, TCF1ALPHA, DKFZp586H0919, LEF-1
NCBI Gene Id 51176
Protein Name Lymphoid enhancer-binding factor 1
Description of Target This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Swissprot Id Q9UJU2
Protein Accession # NP_057353
Nucleotide Accession # BC050632
Molecular Weight 39
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express LEF1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express LEF1.
Protein Interactions RNF138; UBC; RNF14; NLK; NARF; STAT5A; PITX2; CTNNB1; CDX1; DPYSL2; nrarp; FHIT; MITF; HINT1; TLE2; TLE1; SETD8; MYB; E2F1; HDAC1; ZBTB3; DACT1; DAZAP2; ALYREF; PIAS4; ALX4; SMAD3; SUMO2; EP300; SMAD1; SMAD2; SMAD4; KPNA1; KPNA2; UBTF; RUNX2; NOTCH1; RUVB
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