Size:1ug
$189.00
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ANA10567
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LEF1 cDNA (ANA10567)

Catalog#: ANA10567
Domestic: within 24 hours delivery | International: 3-5 business days
More Information
Reconstitution and StorageCentrifuge the vials after receiving and add 5 μl ddH2O
TagNone
Datasheets/ManualsPrintable datasheet for anti-LEF1 (ANA10567) antibody
Gene SymbolLEF1
Alias SymbolsTCF10, TCF7L3, FLJ46390, TCF1ALPHA, DKFZp586H0919, LEF-1
NCBI Gene Id51176
Protein NameLymphoid enhancer-binding factor 1
Description of TargetThis gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Swissprot IdQ9UJU2
Protein Accession #NP_057353
Nucleotide Accession #BC050632
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express LEF1.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express LEF1.
Protein InteractionsRNF138; UBC; RNF14; NLK; NARF; STAT5A; PITX2; CTNNB1; CDX1; DPYSL2; nrarp; FHIT; MITF; HINT1; TLE2; TLE1; SETD8; MYB; E2F1; HDAC1; ZBTB3; DACT1; DAZAP2; ALYREF; PIAS4; ALX4; SMAD3; SUMO2; EP300; SMAD1; SMAD2; SMAD4; KPNA1; KPNA2; UBTF; RUNX2; NOTCH1; RUVB
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