Catalog No: OPPA01810 (Formerly GWB-C518F9)
Size:5UG
Price: $75.00
SKU
OPPA01810
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LDHA Protein (OPPA01810)

Datasheets/ManualsPrintable datasheet for OPPA01810
Product Info
Predicted Species ReactivityHuman
Product FormatThe LDHA protein solution contains 20mM Tris-HCl pH-8, 100mM NaCl and 20% glycerol. Physical appearance: Sterile Filtered colorless solution.
HostE. Coli
::Product Introduction: LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential.
Product Description: LDHA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 352 amino acids (1-332 a.a.) and having a molecular mass of 38.8 kDa. The LDHA is fused to a 20 amino acid his tag at N-terminus and purified by conventional chromatography.
Reconstitution and StorageLDHA although stable 4C for 4 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
PurityGreater than 95.0% as determined by SDS-PAGE.
Peptide SequenceMGSSHHHHHH SSGLVPRGSH MATLKDQLIY NLLKEEQTPQ NKITVVGVGA VGMACAISIL MKDLADELAL VDVIEDKLKG EMMDLQHGSL FLRTPKIVSG KDYNVTANSK LVIITAGARQ QEGESRLNLV QRNVNIFKFI IPNVVKYSPN CKLLIVSNPV DILTYVAWKI SGFPKNRVIG SGCNLDSARF RYLMGERLGV HPLSCHGWVL GEHGDSSVPV WSGMNVAGVS LKTLHPDLGT DKDKEQWKEV HKQVVESAYE VIKLKGYTSW AIGLSVADLA ESIMKNLRRV HPVSTMIKGL YGIKDDVFLS VPCILGQNGI SDLVKVTLTS EEEARLKKSA DTLWGIQKEL QF.
Gene SymbolLDHA
Alias SymbolsLDHM, GSD11, PIG19, HEL-S-133P
NCBI Gene Id3939
Protein NameL-lactate dehydrogenase A chain
Description of TargetRecombinant Human Lactate Dehydrogenase A
Uniprot IDP00338
Protein Accession #NP_001158887.1
Protein Size (# AA)Recombinant
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