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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for OAAQ00180 |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Mouse, Rat |
Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
Clonality | Monoclonal |
Clone | LckY505-A3 |
Isotype | Rabbit IgG1k |
Host | Rabbit |
Conjugation | SureLight 488 |
Application | FC |
Reconstitution and Storage | 2-8C |
Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr505 of human phospho Lck |
Purification | Protein A+G |
Target Post-Translational Modification | Phospho-Tyr505 |
Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
Reference | Serafin V, Capuzzo G, Milani G, et al. (2017) Blood. 130: 2750-2761. Lee KC, Ouwehand I, Giannini AL, et al. (2010) Leukemia. 24: 896-900. |
Gene Symbol | LCK |
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Gene Full Name | LCK proto-oncogene, Src family tyrosine kinase |
Alias Symbols | LSK, YT16, IMD22, p56lck, pp58lck |
NCBI Gene Id | 3932 |
Protein Name | tyrosine-protein kinase Lck |
Description of Target | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. |
Uniprot ID | P06239 |
Protein Accession # | NP_001036236.1 |
Nucleotide Accession # | NM_001042771.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)" provided in?
This item is provided in "Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)"?
This target may also be called "LSK, YT16, IMD22, p56lck, pp58lck" in publications.
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What is the shipping cost for "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human LCK Antibody : SureLight 488 (Phospho-Tyr505) (OAAQ00180)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "LCK"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "LCK"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "LCK"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "LCK"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "LCK"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "LCK"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.