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MAP1LC3B Antibody (OAAB13483)

400ul
$390.00
In Stock
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Gene Symbol:
MAP1LC3B
NCBI Gene Id:
81631
Protein Name:
Microtubule-associated proteins 1A/1B light chain 3B
Swissprot Id:
Q9GZQ8
Protein Accession #:
NP_073729.1
Alias Symbols:
MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-associated prote
Replacement Item:
This antibody may replace item sc-129100 from Santa Cruz Biotechnology.
Description of Target:
Purified Rabbit Polyclonal Antibody (Pab)
Molecular Weight:
14688 Da
Host:
Rabbit
Clonality:
Polyclonal
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAP1LC3B.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAP1LC3B.
Immunogen:
This LC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from human LC3.
Predicted Species Reactivity:
Cow, Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Cow; Human; Mouse; Rat
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for OAAB13483
Isotype:
Ig
Application Info:
WB: 1:500
IHC-P: 1:50~100
Additional Information:
Precautions: LC3 Antibody (APG8A/B) is for research use only and not for use in diagnostic or therapeutic procedures.
:::
Function: Involved in formation of autophagosomal vacuoles (autophagosomes)
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Cellular Location: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes
Tissue Location: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver
Publications:

Bhowmik, T; Gomes, A; NKCT1 (purified Naja kaouthia protein toxin) conjugated gold nanoparticles induced Akt/mTOR inactivation mediated autophagic and caspase 3 activated apoptotic cell death in leukemic cell. 121, 86-97 (2016). WB, IHC, Cow, Human, Mouse, Rat 27527270

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