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Catalog No: ARP40847_P050
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ARP40847_P050
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Datasheets/ManualsPrintable datasheet for anti-LARP7 (ARP40847_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human LARP7
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: WQKILVDRQAKLNQPREKKRGTEKLITKAEKIRLAKTQQASKHIRFSEYD
Concentration0.5 mg/ml
Blocking PeptideFor anti-LARP7 (ARP40847_P050) antibody is Catalog # AAP40847 (Previous Catalog # AAPY01099)
ReferenceKrueger,B.J., (2008) Nucleic Acids Res. 36 (7), 2219-2229
Publications

Muniz, L., Egloff, S. & Kiss, T. RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP. Nucleic Acids Res. 41, 4686-98 (2013). 23471002

The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. EMBO J. 36, 934-948 (2017). 28254838

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife. 7, (2018). 29845934

Description
Gene SymbolLARP7
Gene Full NameLa ribonucleoprotein domain family, member 7
Alias SymbolsALAZS, PIP7S, hLARP7, HDCMA18P
NCBI Gene Id51574
Protein NameLa-related protein 7
Description of TargetThe function remains unknown.
Uniprot IDQ4G0J3
Protein Accession #NP_056269
Nucleotide Accession #NM_015454
Protein Size (# AA)582
Molecular Weight67kDa
Protein InteractionsHEXIM1; AFF1; CDK9; CCNT1; UBC; LIN28B; LIN28A; MEPCE; RNF2; VCPIP1; RABEP2; BRCC3; RPP25; CD2AP; JMJD6; HNRNPR; TRIM28; HUWE1; MTA2; SPAG9; TSC22D1; HDAC1; NR3C1; RN7SK; RPS16; HNRNPA1; CSNK2A1; tat; PAXIP1; BARD1; APP; CAND1; SIRT7; PRPF40A; Ybx1; Nhp2l
  1. What is the species homology for "LARP7 Antibody - C-terminal region (ARP40847_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "LARP7 Antibody - C-terminal region (ARP40847_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "LARP7 Antibody - C-terminal region (ARP40847_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "LARP7 Antibody - C-terminal region (ARP40847_P050)"?

    This target may also be called "ALAZS, PIP7S, hLARP7, HDCMA18P" in publications.

  5. What is the shipping cost for "LARP7 Antibody - C-terminal region (ARP40847_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "LARP7 Antibody - C-terminal region (ARP40847_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "LARP7 Antibody - C-terminal region (ARP40847_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "67kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "LARP7 Antibody - C-terminal region (ARP40847_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "LARP7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "LARP7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "LARP7"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "LARP7"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "LARP7"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "LARP7"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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