LAMA3 Antibody (OAAF03029)

Catalog No: OAAF03029 (Formerly GWB-ASE183)

Size:100 ug

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using LAMA3 Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of HepG2 cells, using LAMA3 Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid PBS (without Mg2+ and Ca2+), pH 7.4, 0.5% BSA, 0.02% sodium azide and 50% glycerol.
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin
• Reconstitution and Storage: Store at -20°C for 1 year.
• Immunogen: The antiserum was produced against synthesized peptide derived from human LAMA3. AA range:2571-2620
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Specificity: LAMA3 antibody detects endogenous levels of total LAMA3 protein.
• Formulation: Rabbit IgG in
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: IHC: 1/100 - 1/300
  IF: 1/200 - 1/1000
  ELISA: 1/10000
• Reference: Ryan M.C., J. Biol. Chem. 269:22779-22787(1994).
  Vidal F., Genomics 30:273-280(1995).
  McLean W.H.I., Hum. Mol. Genet. 12:2395-2409(2003).

Target Info

• Gene Symbol: LAMA3
• Gene Full Name: laminin subunit alpha 3
• Alias Symbols: BM600;BM600 150kD subunit;E170;epiligrin 170 kda subunit;epiligrin alpha 3 subunit;Epiligrin subunit alpha;kalinin 165kD subunit;kalinin subunit alpha;LAM3, alpha-3 subunit;laminin 5, alpha-3 subunit;laminin A3;laminin subunit alpha-3;laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin);laminin-5 alpha 3 chain;laminin-5 subunit alpha;laminin-6 subunit alpha;laminin-7 subunit alpha;LAMNA;LOCS;nicein 150kD subunit;nicein subunit alpha.
• NCBI Gene Id: 3909
• Protein Name: Laminin subunit alpha-3
• Description of Target: The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants.
• Uniprot ID: Q16787
• Protein Accession #: NP_000218.2